Abstract The roughness of fractures may play an important role in affecting the migration and placement of proppants during hydraulic fracturing operations. Previous studies focused on investigating the proppant transport in smooth vertical fractures, which did not consider the effect of the fracture-surface roughness. We examine the migration of proppants in rough and vertical fractures and then quantitatively reveal the effect of roughness on the instantaneous proppant transport and final proppant placement. Two types of rock samples (marble and granite) are fractured with the Brazilian test and molded to manufacture 20 × 20 × 5 cm transparent replicas. The surface roughness of these rock samples was first characterized by fractal dimensions. Then, the dyed fracturing fluid with a given proppant loading was injected into the rough vertical fracture. In each test, the inlet pressures were continuously monitored in order to obtain the differential pressure across the fracture model while the proppants were being transported in the fracture. The process was videotaped to real-time track the proppant distribution in the rough fracture. The proppant-transport behavior in the rough and vertical fracture was observed to be totally different from that in the smooth fracture. The major experimental findings include the following: 1) The proppant in a rough vertical fracture does not progress as a regular sand bank that commonly occurs in the smooth fracture, but rather an irregular-shape sand clusters with fractal characteristics; 2) In the rough and vertical fracture, the phenomenon of proppant bridging is visually observed, and such phenomenon is more likely to occur in the location with a larger roughness height. This implies rough fracture could promote a wider spreading of the proppant in the fracture compared to smooth fractures, and; 3) The existence of roughness enhances the vertical displacement of fluid containing proppants. These effects are also favorable for obtaining a better filling of the proppants in the fracture. Our experimental study reveals the mechanisms of proppant transport and distribution in real vertical fractures under the influence of roughness effect.