Briefly stated, carbon capture and sequestration (CCS) will help us to sustain many of the benefits of using hydrocarbons to generate energy as we move into a carbon-constrained world. Even though the CO2 generated by burning hydrocarbons cannot always be captured easily in some cases (as in oil used for transportation), sequestration of CO2 from other sources (such as coal-fired power stations) can help to create, to some degree, the “headroom” needed for the volumes of CO2 that escape capture. Because of the likely continuing competitive (direct) cost of hydrocarbons and in light of the huge investment in infrastructure already made to deliver them, the combination of fossil fuel use with CCS is likely to be emphasized as a strong complement to strategies involving alternative, nonhydrocarbon sources of energy. Moreover, the exploitation of heavy oil, tar sands, oil shales, and liquids derived from coal for transportation fuel is likely to increase, even though these come with a significantly heavier burden of CO2 than that associated with conventional oil and gas. CCS has the potential to mitigate some of this extra CO2 burden. If we wish to sustain the use of oil, gas, and coal to meet energy demands in a carbon-constrained world and to provide time to move toward alternative energy sources, then it will be necessary to plan for and implement CCS over the coming decades. Subsequently, we should expect a continued need for CCS beyond the end of the century.