Operators continue to look to prolific high-permeability, clastic reservoirs in basins around the world. The use of high-deviation and horizontal well trajectories in these fields improves productivity but increases the challenges of sand control. Multilayered metal-mesh screens (MMSs) are widely used as standalone screens for sand control in unconsolidated formations. It is often found that screens with the same filter-layer nominal rating perform differently. This paper presents a combined experimental and numerical-modeling study on sand-screen performance.